As we age, plaque can build up in the blood vessels of the legs. This causes the arteries to narrow, which reduces blood flow and may lead to pain or weakness in the legs and/or feet. As this condition progresses, blood flow to the legs and feet can become severely reduced sometimes causing advanced Peripheral Arterial Disease (PAD), also called Critical Limb Ischemia (CLI). Critical Limb Ischemia prevents the legs and feet from receiving oxygen and nutrients needed for proper function. This severe lack of blood flow can lead to painful legs while walking or at rest and can result in foot sores, ulcers, gangrene, and even amputation.
Fortunately, current medical and surgical procedures can improve the blood flow in many patients using
bypass operations, stents, or other techniques. The bad news is that these techniques have their limits
and many people suffering from limb ischemia are not candidates for conventional treatments.
If you suffer from Critical Limb Ischemia and have been told by a physician that you are no longer
a candidate for surgical or other interventional treatment, you may be eligible for a research
study of an investigational treatment. The treatment involves injecting cells from your own bone
marrow into your leg to possibly improve blood flow. To learn more about this clinical study, and
to see if you might qualify, please click here.